En
  • دکتری (1375)

    زیست شناسی گیاهی

    انستیتو ناسیونال پلی تکنیک - مدرسه عالی مهندسی کشاورزی ، تولوز، فرانسه

  • کارشناسی‌ارشد (1372)

    مهندسی کشاورزی ، اصلاح نباتات

    فرانسه، تولوز، فرانسه

  • کارشناسی (1367)

    مهندسی کشاورزی ، زراعت و اصلاح نباتات

    تهران، تهران، ایران

  • هاپلوئیدی از طریق آندروژنز، القای پلی‌پلوئیدی
  • تولید متابولیت‌های ثانویه دارویی از طریق کشت ریشه‌های مویین و سوسپانسیون سلولی

    دكتر احمد معینی متولد 1343 درجه كارشناسي را در رشته زراعت و اصلاح‌نباتات در سال 1367 از دانشگاه تهران، درجه كارشناسي‌ارشد با گرایش اصلاح‌نباتات در سال 1371 از انستیتو ناسیونال پلی تکنیک - مدرسه عالی مهندسی کشاورزی تولوز کشور فرانسه، و درجه دكترا با گرایش بيولوژي سلولي گیاهی در سال 1376 از انستیتو ناسیونال پلی تکنیک - مدرسه عالی مهندسی کشاورزی تولوز کشور فرانسه كسب نمود. او در مهر ماه این سال به هيئت علمي دانشگاه تربيت مدرس پيوست و هم اكنون دانشيار گروه ژنتیک و به‎نژادی گیاهی دانشکده کشاورزی مي‌باشد. زمينه‌هاي تحقيقاتي ايشان شامل: هاپلوئیدی از طریق آندروژنز، القای پلی‌پلوئیدی و تولید متابولیت های ثانویه از طریق کشت ریشه های مویین و سوسپانسیون سلولی در گیاهان دارویی است.

    ارتباط

    رزومه

    A hybrid model based on general regression neural network and fruit fly optimization algorithm for forecasting and optimizing paclitaxel biosynthesis in Corylus avellana cell …

    M Salehi, S Farhadi, A Moieni, N Safaie, M Hesami
    Journal Papers , , {Pages }

    Abstract

    Bottleneck Removal of Paclitaxel Biosynthetic Pathway By Overexpression of DBTNBT Gene Under Methyl-β-Cyclodextrin and Coronatine Elicitation in Taxus Baccata L.

    K Kashani, MS Sabet, MJ Javaran, A Moieni
    Journal Papers , , {Pages }

    Abstract

    Field-grown donor plants and arabinogalactan proteins improve microspore embryogenesis in sweet pepper (Capsicum annuum L.)

    A Pourmohammad, A Moieni, H Dehghani, SR Monfared
    Journal Papers , , {Pages }

    Abstract

    Study on the factors effective in callus induction in grape

    F Kabiri, A Moieni, A Baghizadeh, Z Movahedi
    Journal Papers , , {Pages }

    Abstract

    Identification of a defense response gene involved in signaling pathways against PVA and PVY in potato

    Z Osmani, MS Sabet, KS Nakahara, A Mokhtassi-Bidgoli, K Vahabi, ...
    Journal Papers , , {Pages }

    Abstract

    Improving diosgenin production and its biosynthesis in Trigonella foenum-graecum L. hairy root cultures

    Farnaz Zolfaghari, Sajad Rashidi-Monfared, Ahmad Moieni, Davar Abedini, Amin Ebrahimi
    Journal PapersIndustrial Crops and Products , Volume 145 , 2020 March 1, {Pages 112075 }

    Abstract

    Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A. rhizogenes strains, including ATCC15834, R1000, A4 and C58, on diosgenin biosynthesis in high- “Boshruyeh” (23.8 mg/gDW) and low “Hamadan” (6.4 mg/gDW) diosgenin-producing genotypes of fenugreek. Interestingly, comparing the metabolite extracted from both leaves and hairy roots of these genotypes suggested that hairy roots are promising platform to produce scalable amount of diosgenin, producing 143.96 mg/gDW in high diosgenin producing hairy roots (A4-mediated hairy roots induction in

    Heterologous expression of an acid phosphatase gene and phosphate limitation leads to substantial production of chicoric acid in Echinacea purpurea transgenic?…

    Meisam Salmanzadeh, Mohammad Sadegh Sabet, Ahmad Moieni, Mehdi Homaee
    Journal PapersPlanta , Volume 251 , Issue 1, 2020 January 1, {Pages 31 }

    Abstract

    Main conclusion A high level of the secondary metabolite chicoric acid is produced by intracellular Pi supply and extracellular phosphate limiting in Echinacea purpurea hairy roots. Abstract Chicoric acid (CA) is a secondary metabolite which is gained from Echinacea purpurea. It has been found to be one of the most potent HIV integrase inhibitors with antioxidant and anti-inflammatory activities. However, the low-biosynthesis level of this valuable compound becomes an inevitable obstacle limiting further commercialization. Environmental stresses, such as phosphorus (Pi) deficiency, stimulate the synthesis of chemical metabolites, bu

    fungal cell Wall and Methyl-β–cyclodextrin Synergistically enhance paclitaxel Biosynthesis and Secretion in Corylus avellana cell Suspension culture

    Siamak Farhadi, Ahmad Moieni, Naser Safaie, Mohammad Sadegh Sabet, Mina Salehi
    Journal PapersScientific reports , Volume 10 , Issue 1, 2020 March 25, {Pages 10-Jan }

    Abstract

    Paclitaxel is the top-selling chemotherapeutic drug used for the treatment of lung, ovarian and breast cancer as well as Kaposi’s sarcoma. Cell suspension culture (CSC) of Corylus avellana has been addressed as a promising alternative for producing paclitaxel. In this study, endophytic fungus strain YEF 33 was isolated from Taxus baccata and identified as Coniothyrium palmarum. The effects of the elicitors derived from this fungus including cell extract, culture filtrate and cell wall (CW) and also chitin, alone or in combination with Methyl-β-Cyclodextrin (MBCD), on paclitaxel biosynthesis in C. avellana CSC were assayed for the first time. CW of C. palmarum was the most efficient fungal elicitor for paclitaxel biosynthesis in C. avella

    Modeling of paclitaxel biosynthesis elicitation in Corylus avellana cell culture using adaptive neuro-fuzzy inference system-genetic algorithm (ANFIS-GA) and?…

    Siamak Farhadi, Mina Salehi, Ahmad Moieni, Naser Safaie, Mohammad Sadegh Sabet
    Journal PapersPlos one , Volume 15 , Issue 8, 2020 August 27, {Pages e0237478 }

    Abstract

    Paclitaxel as a microtubule-stabilizing agent is widely used for the treatment of a vast range of cancers. Corylus avellana cell suspension culture (CSC) is a promising strategy for paclitaxel production. Elicitation of paclitaxel biosynthesis pathway is a key approach for improving its production in cell culture. However, optimization of this process is time-consuming and costly. Modeling of paclitaxel elicitation process can be helpful to predict the optimal condition for its high production in cell culture. The objective of this study was modeling and forecasting paclitaxel biosynthesis in C. avellana cell culture responding cell extract (CE), culture filtrate (CF) and cell wall (CW) derived from endophytic fungus, either individually or

    Mathematical modeling of growth and paclitaxel biosynthesis in Corylus avellana cell culture responding to fungal elicitors using multilayer perceptron-genetic algorithm

    Mina Salehi, Siamak Farhadi, Ahmad Moieni, Naser Safaie, Hamed Ahmadi
    Journal PapersFrontiers in plant science , Volume 11 , 2020 January , {Pages }

    Abstract

    Paclitaxel is the top-selling anticancer medicine in the world. In vitro culture of Corylus avellana has been made known as a promising and inexpensive strategy for producing paclitaxel. Fungal elicitors have been named as the most efficient strategy for enhancing the biosynthesis of secondary metabolites in plant cell culture. In this study, endophytic fungal strain HEF 17 was isolated from C. avellana and identified as Camarosporomyces flavigenus. C. avellana cell suspension culture (CSC) elicited with cell extract (CE) and culture filtrate (CF) derived from strain HEF 17, either individually or combined treatment, in mid and late log phase was processed for modeling and optimizing growth and paclitaxel biosynthesis regarding CE and CF co

    Whole fungal elicitors boost paclitaxel biosynthesis induction in Corylus avellana cell culture

    Mina Salehi, Ahmad Moieni, Naser Safaie, Siamak Farhadi
    Journal PapersPlos one , Volume 15 , Issue 7, 2020 July 16, {Pages e0236191 }

    Abstract

    Paclitaxel is an effective natural-source chemotherapeutic agent commonly applied to treat a vast range of cancers. In vitro Corylus avellana culture has been reported as a promising and inexpensive system for paclitaxel production. Fungal elicitors have been made known as the most efficient strategy for the biosynthesis induction of secondary metabolites in plant in vitro culture. In this research, C. avellana cell suspension culture (CSC) was exposed to cell extract (CE) and culture filtrate (CF) derived from Camarosporomyces flavigenus, either individually or combined treatment, in mid and late log phase. There is no report on the use of whole fungal elicitors (the combined treatment of CE and CF) for the elicitation of secondary metabol

    The Critical Role of AtPAP17 and AtPAP26 Genes in Arabidopsis Phosphate Compensation Network

    Chilak Siamak, Mohammad Sadegh Sabet, Mohammad ALi Malboobi, Ahmad Moieni
    Journal PapersFrontiers in plant science , Volume 11 , 2020 January , {Pages 1495 }

    Abstract

    Purple acid phosphatases (PAP)-encoding genes form a complex network that play a critical role in plant phosphate (Pi) homeostasis. Mostly, the functions of PAPs were investigated individually. However, the interactions of most of these genes in response to various concentrations of available Pi remain unknown. In this study, the roles of AtPAP17 and AtPAP26 genes, and their relationship within Pi homeostasis context were investigated. Surprisingly, atpap17 and atpap26 mutants not only showed no obvious developmental defects, but also produced higher biomass in compare to wild type (WT) plants under normal growth conditions. Comparing gene expression patterns of these mutants with WT plant, we identified a set of genes up-regulated in mutan

    Identification of a defense response gene involved in signaling pathways against PVA and PVY in potato

    Zhila Osmani, Mohammad Sadegh Sabet, Kenji S Nakahara, Ali Mokhtassi-Bidgoli, Khabat Vahabi, Ahmad Moieni, Masoud Shams-Bakhsh
    Journal PapersGM Crops & Food , Volume 12 , Issue 1, 2020 October 7, {Pages 86-105 }

    Abstract

    Potato is the most important non-grain food crop in the world. Viruses, particularly potato virus Y (PVY) and potato virus A (PVA), are among the major agricultural pathogens causing severe reduction in potato yield and quality worldwide. Virus infection induces host factors to interfere with its infection cycle. Evaluation of these factors facilitates the development of intrinsic resistance to plant viruses. In this study, a small G-protein as one of the critical signaling factors was evaluated in plant response to PVY and PVA to enhance resistance. For this purpose, the gene expression dataset of G-proteins in potato plant under five biotic (viruses, bacteria, fungi, nematodes, and insects) and four abiotic (cold, heat, salin

    Heterologous expression of an acid phosphatase gene and phosphate limitation leads to substantial production of chicoric acid in Echinacea purpurea transgenic?…

    Meisam Salmanzadeh, Mohammad Sadegh Sabet, Ahmad Moieni, Mehdi Homaee
    Journal PapersPlanta , Volume 251 , Issue 1, 2020 January 1, {Pages 31 }

    Abstract

    Main conclusion A high level of the secondary metabolite chicoric acid is produced by intracellular Pi supply and extracellular phosphate limiting in Echinacea purpurea hairy roots. Abstract Chicoric acid (CA) is a secondary metabolite which is gained from Echinacea purpurea. It has been found to be one of the most potent HIV integrase inhibitors with antioxidant and anti-inflammatory activities. However, the low-biosynthesis level of this valuable compound becomes an inevitable obstacle limiting further commercialization. Environmental stresses, such as phosphorus (Pi) deficiency, stimulate the synthesis of chemical metabolites, bu

    Modeling of paclitaxel biosynthesis elicitation in Corylus avellana cell culture using adaptive neuro-fuzzy inference system-genetic algorithm (ANFIS-GA) and …

    S Farhadi, M Salehi, A Moieni, N Safaie, MS Sabet
    Journal Papers , , {Pages }

    Abstract

    Whole fungal elicitors boost paclitaxel biosynthesis induction in Corylus avellana cell culture

    M Salehi, A Moieni, N Safaie, S Farhadi
    Journal Papers , , {Pages }

    Abstract

    Efficient silencing gene construct for resistance to multiple common bean (Phaseolus vulgaris L.) viruses

    A Azizi, J Verchot, A Moieni, M Shams-Bakhsh
    Journal Papers , , {Pages }

    Abstract

    Fungal cell wall and methyl-β–cyclodextrin synergistically enhance paclitaxel biosynthesis and secretion in Corylus avellana cell suspension culture

    S Farhadi, A Moieni, N Safaie, MS Sabet, M Salehi
    Journal Papers , , {Pages }

    Abstract

    Improving diosgenin production and its biosynthesis in Trigonella foenum-graecum L. hairy root cultures

    F Zolfaghari, S Rashidi-Monfared, A Moieni, D Abedini, A Ebrahimi
    Journal Papers , , {Pages }

    Abstract

    Effect of Two Phosphatase AtPAP17 and AtPAP26 Gene Knockout on Growth Period Duration and Flowering in Arabidopsis thaliana

    S Farhadi, MS Sabet, A Moieni, MA Malboobi
    Journal Papers , , {Pages }

    Abstract

    دروس نیمسال جاری

    • كارشناسي ارشد
      كشت سلول و بافت گياهي ( واحد)
      دانشکده کشاورزی، گروه ژنتيك و به نژادي گياهي
    • كارشناسي ارشد
      كشت سلول و بافت گياهي ( واحد)
    • كارشناسي ارشد
      به نژادي گياهي پيشرفته ( واحد)

    دروس نیمسال قبل

    • كارشناسي ارشد
      كشت سلول و بافت گياهي ( واحد)
      دانشکده کشاورزی، گروه بيوتكنولوژي كشاورزي
    • كارشناسي ارشد
      كشت سلول و بافت گياهي ( واحد)
    • مینا , صالحی
    • 1396
      اشجعي رازليق, فرشته
      بررسي پاسخ به كشت ميكروسپور در بادمجان ( ارقام بلن و دنيز)
    • 1396
      خليلي, سهيلا
    • 1397
      عليزاده, عليرضا
    • 1398
      سليمي قلعه تكي, مرضيه
    • 1398
      روزجك, نسترن
    • 1393
      پورمحمد, اعظم
      بررسي توليد جنين، گياهان هاپلوئيد و دايلدها پلوئيد فلفل دلمه اي از طريق كشت ميكروسپورهاي جدا سازي شده
    • 1394
      هاشمي عباس ابادي, مژگان
    • 1396
      فرضي فردكامبلاش, ولي
    • 1396
      عليميرزايي, مريم
    • معاون اداری مالی دانشکده کشاورزی
    • مدیر گروه اصلاح نباتات (1378-1376)
    • مدیر گروه اصلاح نباتات (1380-1378)
      داده ای یافت نشد

    مهم

    جدید

      اطلاعیه ای درج نشده است