Maryam Nikkhah
Associate Professor
Speciality: Protein Self Assembly-Protein engineering
  • BS/BA: Cell and Molecular Biology
  • MS: Biophysics
  • PhD: Biophysics
  • Phone: 82884734
  • Fax: 82884457
  • Email: m_nikkhah@modares.ac.ir
  • Address: School of Biological Sciences, Tarbiat Modares University
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Maryam Nikkhah
 
Academic Status: Assistant Professor
 

Address: Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University Tehran, Iran P.O.Box:14115-154
Phone:
+98 (21) 82884734
Fax: :+98(21) 82884717
Email: m_nikkhah@modares.ac.ir
 
Education and Degrees:
 
·         B.Sc: 1992-1996 Cell and Molecular Biology, Department of Biology, Faculty of basic sciences, University of Tehran, Tehran, Iran
  • M.Sc: 1996-1999 Biophysics, Institute of Biochemistry and Biophysics, University of Tehran, Iran.
  • PhD: 1999-2006 Biophysics, Institute of Biochemistry and Biophysics, University of Tehran, Iran.

 Short-Term Fellowships:
Protein Engineering, Biochemistry Department, University of Cambridge, UK, 2000-2001.
 

 Courses Taught:
 
 - Identification Methods in Nanobiostructures, to PhD Students
- Bioengineering, to PhD Students
- Cell Culture and Molecular Biology, to PhD Students
- Biophotonics, to PhD Students

 
 International Publications:
 
1- Maryam Nikkhah, Hossein Naderi-Manesh, Majid Taghdir , Mehdi Talebzadeh , Majid Sadeghi-Zadeh,   Janatan Schaller and Mohamad N. Sarbolouki. cDNA Cloning, Sequence Analysis and Molecular Modeling of a New Peptide from the Scorpion Buthotus saulcyi Venom.    J.Biochem. Mol.Biol.Vol. 39, No. 3, (2006), 284-291.
2- Maryam Nikkhah, Zahra Jawad-Alami , Mykhaylo Demydchuk , Duncan Ribbons, Massimo Paoli Engineering of β-propeller protein scaffolds by multiple gene duplication and fusion of an idealized WD repeat. Biomolecular Engineering 23 (2006) 185–194.
3- Maryam Nikkhah, Hossein Naderi-Manesh, MohamadN. Sarbolouki, Bijan. Ranjbar, Efficient In Vitro Refolding and Characterization of a New Peptide from the Scorpion Buthotus saulcyi Venom Produced in Escherichia coli, Protein & peptide letters, 13(7), (2006), 459-464.
4- Bagher Said Alipour, Saman Hosseinkhani, Maryam Nikkhah, Hossein Naderi-Manesh, Mohammad Javad Chaichi, Shahroukh Kazempour Osaloo, Molecular cloning, sequence analysis, and expression of a cDNA encoding the luciferase from the glow-worm, Lampyris turkestanicus, Biochemical and Biophysical Research communication 325 (2004) 215-222.
5- Abdo Rahman Emamzadeh, Saman Hosseinkhani, Majid Sadeghizadeh, Maryam Nikkhah, Mohammad Javad Chaichi and Mojtaba Mortazavi, cDNA Cloning, Expression and Homology Modeling of a Luciferase from the Firefly Lampyroidea maculate. Journal of Biochemistry and Molecular Biology, 39(5), (2006), 578-585.
6- Soheila Mohammadi, Maryam Nikkhah, Mahboobeh Nazari,Saman Hosseinkhani, Design of a Coupled Bioluminescent Assay for a Recombinant Pyruvate Kinase from a Thermophilic Geobacillus, Photochemistry and Photobiology, 87(6), (2011), 1338-1345.
7- Hamid Reza Samadikhah, Asia Majidi, Maryam Nikkhah, Saman Hosseinkhani. Preparation, characterization and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes, International Journal of Nanomedicine, 2011(6), 2275 – 2283.
8- Nasrin Navab Safa, Hamid Ghomi, Maryam Nikkhah, Soheila Mohades, Saeed GhasemiOn the Effect of BCD plasma on the Bacteria Cell Membrane,Plasma Science and Technology,  ID: 2011-267.
9- Torkzadeh-Mahani M, Ataei F, Nikkhah M, Hosseinkhani S. Design and development of a whole-cell luminescent biosensor for detection of early-stage of apoptosis, Biosens Bioelectron. 2012 ;38 (1):362-8.

Selected Abstracts:
1-      Hosseinkhani, S. Said alipour, B., Nikkhah, M., Naderi-Manesh, M., Sadeghi-Zadeh, M., Naderi-Manesh, H., and Chaichi, M.J. Molecular cloning and expression of a cDNA encoding the luciferases from the firefly, Lampyris turkestanicus. Luminescence, 2004; 19:146.
2-      Said alipour, B., Hosseinkhani, S. Nikkhah, M., Naderi-Manesh, M., and Chaichi, M.J. cloning and sequencing of Lampyris turkestanicus luciferases. 12th national Biology conference, 2004, Hamadan, Iran.
3-       A. Rahman Emamzadeh, Saman Hosseinkhani, Maryam Nikkhah, Majid Sadeghizadeh, Mohamad Javad Chaichi. Molecular cloning and expression of a cDNA encoding the luciferase from the firefly lampyroide maculate. 8th Iranian Congress of Biochemistry and the 1th International Congress of Biochemistry and Molecular Biology. Sept. 11-15, 2005. Tehran, Iran.
4-      A. Rahman Emamzadeh, Saman Hosseinkhani, Majid Sadeghizadeh, Maryam Nikkhah, Mohamad Javad Chaichi, Mojtaba Mortazavi. Cloning and characterization of a firefly luciferase from the lampyroide maculate. 14th national & 2th International conference of Biology, 2006, Tarbiat modares university, Tehran, Iran.
5-      Soheila Mohammadi, Maryam Nikkhah, Mahboobe Nazari,Saman Khosseinkhani. Expression, purification and characterization of pyruvate kinase from thermophilic Geobacillus sp and coupled bioluminescent assay for ADP measurement. Journal of the Iranian Chemical Society, Vol. 7, Suppl. 1, February 2010.
6-      Azarakhsh Abbasabadi Oladzad, Maryam Nikkhah, Saman Hosseinkhani. Analysis of human SOD1 oligomerization in native and mutant forms (D102N and L127S]. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry & Molecular Biology, Mashhad, Sept. 2011, 6-9.
7-      Asiye Sadat Javanian, Nikkhah Maryam, Hosseinkhani Saman. Site directed mutagenesis of SOD1 (Gly72Ser) and analysis of mutant proteins oligomerization. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry & Molecular Biology, Mashhad, Sept. 2011, 6-9.
8-      Zahra Sadat Saghaeian, Nahid Saghaiyan, Maryam Nikkhah, Majid Sadeghizadeh. Study of Effect of the Mutation Amino Acidis 18 and 125 on Specific Biological Activity of Human Interlukin-2. The First International & 11th Iran Biophysical Chemistry Conference, 13-15 June 2012, Ardabil University of Medical Sciences, Ardabil, Iran.
9-      Masoud Torkzadeh-Mahani, Somayeh Karimzadeh, Farangis Ataei, Mojtaba Mortezavi, Maryam Nikkhah, Saman Hosseinkhani. Expression of Recombinant Apaf-1 in Pichia Pastoris. The First International & 11th Iran Biophysical Chemistry Conference, 13-15 June 2012, Ardabil University of Medical Sciences, Ardabil, Iran.
10- Mohammad Salehi Aliabad Olia, Maryam Nikkhah, Saman Hosseinkhani. Copper/ zinc-superoxide Dismutase 1 Mutants and the Propensity to Oligomerization. The First International & 11th Iran Biophysical Chemistry Conference, 13-15 June 2012, Ardabil University of Medical Sciences, Ardabil, Iran.
11- Shahriar Mirpour, Maryam Nikkhah, Somayeh Pirouzmand, Hamid Reza Ghomi. Effect of non-thermal atmospheric pressure plasma jet on human breast cancer cell. Bulletin of the American Physical Society (APS)-65th Annual Gaseous Electronics Conference, Volume 57, Number 8, October 22-26, 2012, Austin, Texas.
12- Tahere Tajik, Maryam Nikkhah, Abdolahi Shojaian. Biological Synthesis of Gold Nanoparticles Using Leaf Extract of Basil (Ocimum bacilicum). 1st NANO Technology and Itʾs Application in Agriculture and Natural Recources Conference, 15-16 May 2012 , Tehran-Karaj.
13- Tahere Tajik, Maryam Nikkhah, Abdolahi Shojaian. Investigation on the toxicity effects of synthesized gold nanoparticles by biological method on MCF-7 cell line. The 17th National and 5th International Iranian Biology Conference, September 4-6 2012-Kerman, Iran.
14- Rohani, N., Karimi Torshizi, M. A., Nikkhah, M. Production of novel poultry products and occupation of poultry science educators. 2011.
15- N. Rohani, M. A. Karimi Torshizi, M. Nikkhah. Effect of dietary supplementation of arginine, asparagines and methionine on performance and egg quantitative traits in Japanese quailʾs eg. 2012.
16- Yarbakht, M., Jalali javaran, M., Nikkhah, M., Mohebodini, M. Study of pro- insulin gene expression in E.coli by using chloroplast vector Pkcz. 12th Iranian Genetics Congress. May 2012.
17- Yarbakht, M., Jalali javaran, M., Nikkhah, M., Mohebodini, M. Study of human Pro- insulin gene expression in transplastomic tobacco. 12th Iranian Genetics Congress. May 2012.