Medical Sciences

Education

1.

BSc/BA; Microbiology, Isfahan University, Iran, 1990

2.

MS; Mycology, Tarbiat Modares University, Iran, 1990-1993

3.

PhD; Mycology, Tarbiat Modares University, Iran, 1994 –1999. 
Title of thesis : Comparison of antigenic structure of Microsporum canis and M.equinum and their role in humoral and cellular Immune responsses

4.

Post-Doctoral Fellowship, Dept. of Metabolic Regulation Laboratory, National Food Research Institute. Tsukuba, Japan, 2005-2007.

Research Experience

1.

Identification and differentiation of fungal species from clinical samples by molecular techniques.

2.

Identification and purification of antifungal compounds and mycotoxin inhibitors from natural sources.

3.

Production and characterization of hybridoma based anti-aflatoxin B1 monoclonal antibodies and their application in elisa and immunoaffinity techniques.

4.

Antifungal susceptibility of natural compounds against pathogenic fungi.

Teaching Experience

1.

Advanced and applied mycology, Mycology, Ph.D students

2.

Advanced and applied mycology, Parasitology, Ph.D students

3.

Elementary mycology, Mycology, M.Sc students

4.

Superficial-Cutaneous mycosis, Mycology, M.Sc students

5.

Sub cutaneous- Mucocutaneous mycosis, Mycology, M.Sc students

6.

Disseminated (viseral) mycosis, Mycology, M.Sc students

7.

Culture of fungi, Mycology, M.Sc students

8.

Experimental animal model, Mycology, M.Sc students

9.

Antifungal drugs and the mechanisms of action, Mycology, Ph.D students

Languages Skills

1.

Persian

2.

English

3.

Japanese

Awards

1.

Young scientist, Chinese Congress of Clinical Chemistry & Laboratory Medicine , Hong Kong, China, 2000, Chinese Congress of Clinical Chemistry & Laboratory Medicine 2000, 11 – 15 June 2000, Hong Kong, China.

2.

Young scientist, The 7th International Mycological Congress, Oslo, Norway, 2002, The 7th International Mycological Congress, 11 – 17 August 2002, Oslo, Norway.

3.

Excellent poster, 10th International Congress of Culture Collections (ICCC-10), Tsukuba, Japan, 2004

Organizer

1.    The first workshop in Advanced Techniques in Medical Mycology, 23-25 June 2001, Tarbiat Modares University, Tehran, Iran.

2.    The workshop of Basic Molecular Techniques in Mycology , 18 – 20 December 2002, Damghan Applied High Education Institute , Damghan , Iran.

3.    PCR and its Application in Veterinary Medicine, 17-18 February 2004, TAT Organization, Tehran, Iran.

Books

1.

General Veterinar Mycology, Ministry of Jahad Agriculture. 2005

2.

Marine Mycolog and Mycotic Diseases, Ministry of Jahad Agriculture. 2005

3.

Veterinary Mycotic Diseases, Ministry of Jahad Agriculture. 2005

4.

Natural Aflatoxins Inhibitors from Medicinal Plants; Chapter 19 In: Mycotoxins in Food, Feed and Bioweapons. Springer-Verlag. 2011.

5.

Aflatoxins: mechanisms of inhibition by antagonistic plants and microorganisms; Chapter 14 In: Aflatoxins: Biochemistry and Molecular Biology. In-Tech. 2011.

6.

Natural Inhibitors of Food-borne Fungi from Plants and Microorganisms; Chapter 13 In: Natural Antimicrobials in Food Safety and Quality. CABI International. 2011.

7.

Aflatoxins; Public Health and Agricultural Significance. Ministry of Jahad Agriculture. 2011.

National Journals

1.

1995, 'Identification and purification of Aspergillus fumigates antigens and their effects on inducing humoral responses in animal models', Gashtak, Vol. 3, No. 2, pp. 31-36

2.

1999, 'SDS-Page separation of dermatophyte antigens and western blotting in experimental animal model and human dermatophytosis', Kowsar Medical Journal, , Vol. 4, No. 4, pp. 229-235

3.

2001, '.Identification of Malassezia species in patients with pityriasis versicolor submitted to the Razi hospital in Tehran', Iranian Biomedical Journal, Vol. 5, No. 4, pp. 121-126

4.

2000, 'Screening of aflatoxin – producing mould isolates based on fluorescence production on a specific medium under ultraviolet light', Acta Medica Iranica , Vol. 38, No. 2, pp. 67-73

5.

2003, 'Inhibitory effects of aqueous onion and garlic extracts on growth and keratinase activity in Trichophyton mentagrophytes', Iranian Biomedical Journal, Vol. 7, No. 3, pp. 113-18

6.

2000, 'Using of simple methods for identification of toxigenic strains of Aspergillus flavus and A.parasiticus by U.V. photography', Modares Medical journal , Vol. 3, No. 2, pp. 103-109

7.

2003, 'Cellobiose dehydrogenase production by the genus of Cladosporium.', Iranian Biomedical Journal, Vol. 8, No. 2, pp. 107-111

8.

2004, 'Screening of soil and sheep faecal samples for preducious fungi:isolation and characterization of the nematode-trapping fungus Arthrobotrys oligospora',Iranian Biomedical Journal , Vol. 8, No. 3, pp. 135-142

9.

2004, 'Effects of aqueous and essential oil of onion (Allium cepa) on growth and lipase activity in Malassezia furfur', Daneshvar Medicine , Vol. 11, No. 52, pp. 31-38

10.

2004, 'Rapid identification of Malassezia furfur from other Malassezia species: A major causative agent of pityriasis versicolor', Iranian Journal of Medical Sciences , Vol. 29, No. 1, pp. 36-39

11.

2005, 'Effect on incubation time on Aspergillus parasiticus growth and its aflatoxin productivity in presence of neem (Azadirachta indica A. juss)', Hakim Medical Journal , Vol. 8, No. 3, pp. 54-60

12.

2006, 'Comparative study of the effect of antifungal drugs terbinafine and ketoconazole against Malassezia furfur isolates', Daneshvar Medicine , Vol. 14, No. 66, pp. 45-52

13.

2006, 'Comparative study on In vitro antifungal activity of garlic (Allium sativum) , onion (Allium cepa) and terbinafine against current dermatophytes species',Daneshvar Medicine, Vol. 13, No. 62, pp. 35-42

14.

2005, 'Phenotypic diagnostic methods to distinguish of Candida dubliniensis from C.albicans', Kowsar Medical Journal, Vol. 10, No. 4, pp. 247-254

15.

2006, 'In vitro antifungal activities of griseofulvin and terbinafine against common dermatophytes', Hakim Medical Journal, Vol. 9, No. 1, pp. 28-33

16.

2006, 'Antifungal activity of Boswellia serrata's essential oil against fluconazole resistant and susceptible isolates of Candida albicans', Medical Journal of Isfahan , Vol. 24, No. 82, pp. 30-35

17.

2007, 'Identification and diagnosis of common Malassezia species by PCR-RFLP in IRAN', Modares Medical journal, Vol. 9, No. 1, pp. 37-43

18.

2008, 'Evaluation of Disk Diffusion and Broth Microdilution Methods for Fluconazole Susceptibility Testing in one Group of Candida spp. in Tehran', Daneshvar Medicine , Vol. 15, No. 73, pp. 51-58

19.

2008, 'Antifungal effects of fluconazole, itraconazole and ketoconazole in intact and combination forms against some pathogenic yeasts', Ofogh danesh (Medical Journal of Gonabad university, Vol. 13, No. 4, pp. 29-39

20.

2009, 'Application of PCR-RFLP to rapid identification of the main pathogenic dermatophytes from clinical specimens ',Iranian Journal of Public Health, 38(1) ,18-24

21.

2008, 'Comparative Study of the Major Iranian Cereal Cultivars and some Selected Spices in relation to Support Aspergillus parasiticus Growth and Aflatoxin Production ', Iranian biomedical Journal, Vol. 12, No. 4, pp. 229-236

22.

'Frequency and Identification of Fungal Strains in Patients with Chronic Rhinosinusitis', Iranian Journal of Pathology, Vol. 3, No. 3, pp. 135-139

23.

'Antifungal effects of allium cepa and some azoles in intact forms and in combinations to each other against pathogenic yeasts', Kowsar Medical Journal, Vol. 13, No. 2, pp.

24.

'Antifungal effect of Allium sativum ethier individually or in combination with Fluconazole, Itraconazole and Ketoconazole against pathogenic yeasts', J Gorgan Uni Med Sci, Vol. 11, No. 1, pp. 56-49

25.

2010, "An epidemiological survey on cattle ringworm in dairy farms of Meshhad, Eastern Iran"  Iranian Journal of Microbiology, Vol. 1, No. 3, pp. 31-36.

26.

2011, "Mycobiota and aflatoxin B1 contamination of rainbow trout Oncorhinchus mykiss) feed with emphasis to Aspergillus section Flavi". Iranian Journal of Fisheries.10 (3): 363-374

27.

2011, "Molecular identification of antagonistic bacteria from Tehran soils and evaluation of their inhibitory activities toward pathogenic fungi". Iranian Journal of Microbiology.3 (3): 140-146.

28.

2012, "Effect of curcumin on Aspergillus parasiticus growth and expression of major genes involved in the early and late stages of aflatoxin biosynthesis". Iranian J Publ Health 2012; 41(6):72-79

29.

2013, 'Diversity and distribution patterns of airborne microfungi in indoor and outdoor hospitale nvironments in Khorramabad, Southwest Iran'. Jundishapur Journal of Microbiology 2013, 6 (2): 186-192

International Journals

1.

2001, 'Effect of neem leaf extract on production of aflatoxins and activities of fatty acid synthetase, isocitrate dehydrogenase, and glutathione S-transferase in Aspergillus parasiticus', Mycopathologia, Vol. 154, No. 2, pp. 79-84

2.

2004, 'Morphological evidences for onion-induced growth inhibition of Trichophyton rubrum and Trichophyton mentagrophytes', Fitoterapia , No. 75, pp. 645-655

3.

2005, 'Morphological alterations in toxigenic Aspergillus parasiticus exposed to neem (Azadirachta indica) leaf and seed aqueous extracts', Mycopathologia , No. 159, pp. 565-570

4.

2006, 'In vitro antifungal activities of Allium cepa, Allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes', Fitoterapia , No. 77, pp. 321-323

5.

2006, 'A Survey on Distribution of Aspergillus Section Flavi in Corn Field Soils in Iran: Population Patterns Based on Aflatoxins, Cyclopiazonic Acid and Sclerotia Production', Mycopathologia , Vol. 161, No. 3, pp. 183-192

6.

2006, 'Inhibitory Effects of Akacid®plus on Growth and Aflatoxin Production by Aspergillus parasiticus ', Mycopathologia , Vol. 161, No. 4, pp. 245-249

7.

2006, 'Ultrastructural evidences of growth inhibitory effects of a novel biocide, Akacid(plus), on an aflatoxigenic Aspergillus parasiticus', Toxicon , Vol. 48, No. 8, pp. 1075-1082

8.

2007, 'Biological control of Rhipicephalus (Boophilus) annulatus by different strains of Metarhizium anisopliae, Beauveria bassiana and Lecanicillium psalliotae fungi', Parasitology Research, Vol. 100, No. 6, pp. 1297-1302

9.

2007, 'Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus', Bioscience, Biotechnology and Biochemistry , Vol. 71, No. 9, pp. 2329-2332

10.

2007, 'Study on the effect of neem (Azadirachta indica A. juss) leaf extract on the growth of Aspergillus parasiticus and production of aflatoxin by it at different incubation times', Mycoses, No. 51, pp. 35-39

11.

2008, 'Inhibitory effects of Satureja hortensis L. essential oil on growth and aflatoxin production by Aspergillus parasiticus', International Journal of Food Microbiology, No. 123, pp. 228-233

12.

2009, 'Chemical composition and antiaflatoxigenic activity of Carum carvi L., Thymus vulgaris and Citrus aurantifolia essential oils ', Food control , Vol. 20, No. 2009, pp. 1024-1018

13.

2009, 'Inhibitory Effects of Ephedra major Host on Aspergillus parasiticus Growth and Aflatoxin Production', Mycopathologia, Vol. 2009, No. 168, pp. 249-255

14.

2010, 'Studies on the Effect of Temperature, Incubation Time and in vivo Gut Passage on Survival and Nematophagous Activity  Arthrobotrys oligospora Var. Oligospora and A. cladodes Var. Macroides'. Global Veterinaria 2010. 4 (2): 112-17.

15.

2010, ' Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem'. International Journal of Food Microbiology. 139 (2010): 127–33.

16.

2011, 'A survey on distribiution  and  toxigenicity of  Aspergillus flavus  from  indoor  and  outdoor  hospital environments'. Folia Microbiologica 2011; 56 (6):527-534.

17.

2011, 'Search for novel antifungals from 49 indigenous medicinal plants: Foeniculum vulgare and Platycladus orientalis as strong inhibitors of aflatoxin production by Aspergillus parasiticus'. Annals of Microbiology 2011; 61: 673-681.

18.

2011, 'A 4-year survey of dermatomycoses in Tehran from 2006 to 2009'. Journal de Mycologie Médicale 2011; 21 (4): 260-265.

19.

2012, 'An insight into the distribution, genetic diversity, and mycotoxin production of Aspergillus section Flavi in soils of pistachio orchards'. Folia Microbiologica 2012; 57(1): 27-36.

20.

2012, 'Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens'. Journal de Mycologie Médicale. 2012; 22: 308-315

22.

2013, 'Expression of aflatoxin genes aflO (omtB) and aflQ (ordA) differentiates levels of aflatoxin production by Aspergillus flavus strains from soils of pistachio orchards'. Research in Microbiologoy 2013, 104( 2013): 293-299

Refereed National Conference Proceedings

1.

2001, Asian International Mycological Congress , Karaj, Iran, pp.

2.

2012, 'Inhibitory effects of some native medicinal plants on Aspergillus parasiticus growth and aflatoxin production. Acta Horticulturae: Proceedings of the first International Symposium on Mycotoxins in Nuts and Dried Fruits

3.

2012, 'Inhibition of Aspergillus parasiticus growth and aflatoxin production by antagonistic bacteria isolated from soils of pistachio orchards. Acta Horticulturae: Proceedings of the first International Symposium on Mycotoxins in Nuts and Dried Fruits

Refereed International Conference Proceedings

1.

World Veterinary Congress , Lyon, France, 1999

2.

Chinese Congress of Clinical Chemistry & Laboratory Medicine , Hong Kong, China, 2000

3.

11th European Congress of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey, 2001

4.

11th International Congress of Immunology, Stockholm, Sweden, 2001

5.

Eurotox , Istanbul, Turkey, 2001

6.

9th APCCB & 28th Annual Conference of ACBI, New Delhi, India, 2002

7.

The 7th International Mycological Congress, Oslo, Norway, 2002

8.

'Eurolab 2003, 1-6 June 2003, Barcelona, Spain

9.

'14th European Congress of Mycologists, 22-29 September 2003, Ukraine', 14th European Congress of Mycologists, 22-29 September 2003, Ukraine

10.

' 10th International Congress of Culture Collections (ICCC-10), 10-15 October 2004, Tsukuba, Japan', 10th International Congress of Culture Collections (ICCC-10), 10-15 October 2004, Tsukuba, Japan

11.

'10th Congress of the European Confederation of Medical Mycology, 17-20 July 2004 Wroclaw, Poland', 10th Congress of the European Confederation of Medical Mycology, 17-20 July 2004 Wroclaw, Poland

12.

'2nd Trends in Medical Mycology (TIMM), 23-26 Oct 2005, Berlin, Germany.', 2nd Trends in Medical Mycology (TIMM), 23-26 Oct 2005, Berlin, Germany

13.

'17th congress of International Society for Human and Animal Mycology, 25-29 May 2009, Tokyo, Japan

Memberships in Societies

1.

Iranian Medicine Council, -

2

European Mycological Council , -

3.

Federation European Microbiological Council,

4.

Infectious Diseases Council,

M.Sc. Thesis Supervised

1.

Refaee J, 'The effect of onion extract on growth pattern and lipase activity of Malassezia furfur.', Supervisor

2.

Razafsha M, 'Study on the effects of garllic and onion extracts on growth pattern and keratinase activity of Trichophyton mentagrophytes', Supervisor

3.

Goodarzi M, 'Ultrastructural study of the effect of onion extract on Trichophyton mentagrophytes and T.rubrum', Supervisor

4.

Amirrajab N, 'Antifungal effect of Melia azaderach in comparing griseofulvin and terbinafine against common dermatophytes', Supervisor

5.

Fazli A, 'Study on Cellobiose dehydrogenase production by the genus of Cladosporium', Guidance

6.

Shokohamiri MR, 'In vitro antifungal effects of Melia azadirachta L. , terbinafine and ketoconazole against Malassezia species', Supervisor

7.

Moghadasi B, 'Comparing ketoconazole , terbinafine and Melia azaderach against canidida species isolated from vulvo-vaginitis', Supervisor

8.

Nemati L, 'Evaluation of disk diffusion and broth microdilution methods for fluconazole and ketoconazole susceptibility testing in Candida spp', Supervisor

9.

Razzaghparast A, 'Antifungal activity of Allium sativum and Allium cepa extracts with antifungal drugs against pathogenic yeasts', Supervisor

10.

Amanloo S, 'Molecular Identification of Malassezia species from skin scales by RFLP-PCR', Guidance

11.

Akbari S, 'Antifungal activity of Thymus vulgaris L. and Origanum vulgare L. against fluconazole resistant and susceptible Candida albicans isolates', Supervisor

12.

Mosleh F, 'Investigation on the prevalence of bovine dermatophytosis (ring worm) in Mashad township', Supervisor

13.

Adim R, 'Fusarium species, fumonisins and leukoencephalomalacia in horse', Adviser

14.

Kazeroon shiree AM, 'Study on aflatoxin – producing ability of Aspergillus flavus and Aspergillus parasiticus isolates isolated from soil and sheep fecal samples', Adviser

15.

Tehrani Sharif M, 'Application of anti-aflatoxin polyclonal and monoclonal antibodies in analysis of animal biological samples and agricultural comodities ', Adviser

16.

Ebrahimi M, 'Investigation on fungal flora of soil and small ruminant fecal samples with special reference to nematophagous fungi ', Adviser

17.

Ahangar M, 'Investigation on hair coat fungal flora of cattle and sheep with special reference to ringworm fungi in Garmsar and Amol townships', Adviser

18.

Hosseini A, 'Study of the prevalence of Malassezia species in external ear of cattle and sheep in Garmsar and Amol townships', Adviser

19.

Sheikhi M, 'Study of the effect of Akacid on growth and morphology of toxigenic Aspergillus parasiticus', Adviser

20.

Zare M, 'study of the growth and aflatoxin production by aspergillus parasiticus on corn, wheat and rice as natural substrates', Adviser

21.

Khazaei M, 'Fungal genomics and protomics strategies and application', Adviser

22.

Motevali M, 'Cellular and molecular aspects of virulence factors in pathogenic fungi in veterinary and medicine', Adviser

23.

Moosavi M, 'Isolation, determination and protein pattern determination of Malassezia isolates in Tinea versicolor and seborrhic dermatitis', Adviser

24.

Parsa S, 'Extracellular keratinase characteristics in Trichophyton mentagrophytes isolates obtained from acute and chronic dermatophytosis', Adviser

25.

Azadegan H, 'Identification of SAP2 in different isolates of Candida albicans by using sera of infected mice', Adviser

26.

Katiraee F , 'Isolation and identification of Candida dubliniensis from clinical samples', Adviser

27.

Abedi A, 'Comparison of the biological control of Beauveria bassiana , Metarhizium anisopliae , Verticillium lecanii on Blattella germanica', Adviser

28.

Shahkar L, 'Study of cutaneous dermatophytosis in patients that refered to diagnostic laboratories in Golestan', Adviser

29.

Amani S, 'Study of the role of veA, laeA and aflR in determining morphological characteristics and cyclopiazonic acid production in Aspergillus flavus',Supervisor

30.

Jahanshiri Z, 'Study of the effect of some phenolic compounds, flavonoids and antioxidants on aflatoxin production with special reference to the expression ofaflR, nor1, cypA and ver1 genes in Aspergillus parasiticus', Supervisor

31.

Sepahvand A, 'Molecular typing of Aspergillus section Favi  isolated from air and soil samples of Khoramabad Hospitals with special reference to aflatoxin-producing species', Supervisor

32.

Ranjbariyan AR, 'Isolation and molecular identification of growth inhibitory organisms against some pathogenic fungi', Supervisor

33.

Teifouri F,'Evaluation on Alt a 1 gene expressin and production in Alternaria and related genus and its role on induction of asthma and allergy, Supervisor

34.

Mohamadi N, 'Molecular identification and assessment of genetic diversity of Fusarium species in Gibberella fujikuroi complex fumonisin toxin producing using amplified fragment length polymorphism (AFLP)  and TEF-1α partial gene sequencing', Supervisor

35.

Aghaee S, ' Identification of Aspergillus spp. airborne using morphological and molecular techniques from the air of Tehran', Supervisor

36.

Aslani N, ' Identification of Alternaria spp. airborne using morphological and molecular techniques from Tehran', Supervisor

37.

Afshar H, ' A comparison of Alt a 1 homology between airborne Alternaria spp. isolates', Supervisor

Training course

1-

Training course for "Sample preparation for scanning microscope (SEM) and field emission SEM observation " , 10/12/0182 - 10/12/0184

Technical Skills

1.

Cell culturing

2.

Protein purification methods and chromatography including sieve, ion exchange, affinity,TLC, HPLC,…

3.

Electrophoresis including PAGE, SDS-PAGE, Pulsed-Field Gel Electrophoresis (PFGE)

4.

Immunoassay methods including ELISA, RIA, EIA, Immunoblotting

5.

Southern blot hybridization, Western blot hybridization

6.

PCR, RAPD-PCR, Primer Design

7.

Restriction Fragment Length Polymorphism (RFLP), Amplified Fragment Length Polymorphism (AFLP)

8.

Gene cloning and expression

9.

Sequencing, Sequence analysis

10.

Probe design, Probe preparation

11.

Antifungal susceptibility methods

12.

Analysis of mycotoxins

13.

Electron microscopy