News > With the aim of treating bone infection, controlled drug-delivery system was designed at TMU


 


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With the aim of treating bone infection, controlled drug-delivery system was designed at TMU


University researchers managed to provide a slow-release drug system using Nano-particles to treat bone infection.

Vahid Taghipour Sabzevar, graduate student of chemical engineering in bio-medicine, and executor of the project "Long-term controlled release of vancomycin from in situ formation of poly lactic-glycolic acid, loaded by chitosan nanoparticles”, stated: The advantages of these systems are biodegradability without requiring surgery.

According to Taghipour: The system designed in this study, polymeric nanoparticle system, used in order to reduce the initial release of the drug which results in a prolonged and controlled release of vancomycin; this system can be used for the treatment of chronic bone infection.

He added: “The loading of chitosan nano-particles (containing drugs) in the designed polymer system, compared to the free drug used in these systems; substantially reduced initial release and improved its release time.



13:14 - 2019/06/11    /    number : 10660    /    Show Count : 214



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