Fa
  • Ph.D. (2016)

    Hematology and bloodbanking

    Hematology and bloodbanking, Tarbiat modares university, Tehran, Iran

  • M.Sc. (2011)

    Hematology and bloodbanking

    Hematology and bloodbanking, Tarbiat modares university, Tehran, Iran

  • B.Sc. (2009)

    Lab science

    Paramedicine, Tehran, Tehran, Iran

  • cell therapy in treatment of various disease
  • Tissue engineering
  • Gene therapy

    Contact

    Curriculum Vitae (CV)

    Mesenchymal stem cells derived from perinatal tissues for treatment of critically ill COVID-19-induced ARDS patients: a case series

    Seyed-Mohammad Reza Hashemian, Rasoul Aliannejad, Morteza Zarrabi, Masoud Soleimani, Massoud Vosough, Seyedeh-Esmat Hosseini, Hamed Hossieni, Saeid Heidari Keshel, Zeinab Naderpour, Ensiyeh Hajizadeh-Saffar, Elham Shajareh, Hamidreza Jamaati, Mina Soufi-Z
    Journal PaperStem cell research & therapy , Volume 12 , Issue 1, 2021 December , {Pages 12-Jan }

    Abstract

    Acute respiratory distress syndrome (ARDS) is a fatal complication of coronavirus disease 2019 (COVID-19). There are a few reports of allogeneic human mesenchymal stem cells (MSCs) as a potential treatment for ARDS. In this phase 1 clinical trial, we present the safety, feasibility, and tolerability of the multiple infusions of high dose MSCs, which originated from the placenta and umbilical cord, in critically ill COVID-19-induced ARDS patients. A total of 11 patients diagnosed with COVID-19-induced ARDS who were admitted to the intensive care units (ICUs) of two hospitals enrolled in this study. The patients were critically ill with severe hypoxemia and required mechanical ventilation. The patients received three intravenous infusions (20

    Safety and Feasibility of Autologous Olfactory Ensheathing Cell and Bone Marrow Mesenchymal Stem Cell Co-transplantation in Chronic Human Spinal Cord Injury: A Clinical Trial

    Homa Zamani, Mina Soufizomorrod, Saeed Oraee-Yazdani, Dariush Naviafar, Mohammadhosein Akhlaghpasand, Afsoun Seddighi, Masoud Soleimani
    Journal Paper , 2021 April 27, {Pages }

    Abstract

    Cell-based therapies are considered as promising strategies for spinal cord regeneration. However, a combinatorial cell therapeutic approach seems more bene cial as it can target various aspects of the injury. Here, we assessed the safety and feasibility of autologous mucosal Olfactory Ensheathing Cell (OEC) and bone marrow Mesenchymal Stem Cell (MSC) co-transplantation in patients with chronic, complete (American Spinal Injury Association (ASIA) classi cation A) Spinal Cord Injury (SCI). Three patients with the traumatic SCI of the thoracic level were enrolled. They received autologous OEC and MSC combination through the lumbar puncture. All adverse events and possible functional outcomes were documented performing pre-and post-operative g

    Combining cell therapy with human autologous Schwann cell and bone marrow-derived mesenchymal stem cell in patients with subacute complete spinal cord injury: safety …

    S Oraee-Yazdani, M Akhlaghpasand, M Golmohammadi, M Hafizi, ...
    Journal Paper , , {Pages }

    Abstract

    High expression of long noncoding RNA NORAD is associated with poor clinical outcomes in non-M3 acute myeloid leukemia patients

    MM Eslami, M Soufizomorrod, M Ahmadvand
    Journal Paper , , {Pages }

    Abstract

    Cartilage tissue engineering by co-transplantation of chondrocyte extracellular vesicles and mesenchymal stem cells, entrapped in chitosan-hyaluronic acid hydrogel

    A Heirani-Tabasi, S Hosseinzadeh, S Rabbani, SHA Tafti, K Jamshidi, ...
    Journal Paper , , {Pages }

    Abstract

    Intracerebral Administration of Autologous Mesenchymal Stem Cells as HSV-TK Gene Vehicle for Treatment of Glioblastoma Multiform: Safety and Feasibility Assessment

    S Oraee-Yazdani, M Akhlaghpasand, G Shokri, F Rostami, ...
    Journal Paper , , {Pages }

    Abstract

    Reviewing the role of cardiac exosomes in myocardial repair at a glance

    P Koohsarian, A Talebi, MA Rahnama, MS Zomorrod, S Kaviani, A Jalili
    Journal Paper , , {Pages }

    Abstract

    Cartilage tissue engineering using injectable functionalized Demineralized Bone Matrix scaffold with glucosamine in PVA carrier, cultured in microbioreactor prior to study in …

    N Dadgar, A Ghiaseddin, S Irani, S Rabbani, SHA Tafti, M Soufizomorrod, ...
    Journal Paper , , {Pages }

    Abstract

    Factor V Leiden 1691G> A mutation and the risk of recurrent pregnancy loss (RPL): systematic review and meta-analysis

    Mohammad Masoud Eslami, Mina Soufizomorrod, Saeid Abroun, Bahman Razi
    Journal Paper , Volume 18 , Issue 1, 2020 December , {Pages 16-Jan }

    Abstract

    Although numerous replication case-control studies have attempted to determine the association between Factor V Leiden (FVL) 1691G > A mutation and susceptibility to Recurrent pregnancy loss (RPL), there have been confliction among the results of various ethnic groups. To address this limitation, here we implemented first meta-analysis to provide with consistent conclusion of the association between FVL 1691G > A mutation and RPL risk. After a systematic literature search, pooled odds ratio (OR) and their corresponding 95% confidence interval (CI) were used to evaluate the strength of the association. Additionally, meta-regression analyses were performed to find potential source of heterogeneity. In this meta-analysis, 62 studies, c

    Cartilage Tissue Engineering Using Injectable Functionalized Demineralized Bone Matrix Scaffold with Glucosamine in PVA Carrier, Cultured in Microbioreactor Prior to Study in?…

    Neda Dadgar, Ali Ghiaseddin, Shiva Irani, Shahram Rabbani, Seyed Hossein Ahmadi Tafti, Mina Soufi-zomorrod, Masoud Soleimani
    Journal PaperMaterials Science and Engineering: C , 2020 October 27, {Pages 111677 }

    Abstract

    Using 3D model of injectable scaffolds for cartilage tissue engineering is one of the challenges that should be addressed to avoid invasive surgery for treatment. For this purpose, chondrocytes on Demineralized Bone Matrix (DBM) scaffolds functionalized with glucosamine in 20% polyvinyl alcohol (PVA) as a carrier was applied to the micro-bioreactor in-vitro, then the study was continued on in-vivo stage. Scaffold biocompatibility tests were performed and the mechanical and physicochemical properties were studied showing the fact that DBM was functionalized by Glucosamine, scaffold degradation rate was 53% after 720 hours and swelling ratio was 2.5 times after 16 hours, injectable scaffold demonstrated better mechanical characteristics (P <

    The role of cardiac exosomes in myocardial repair at the glance

    Parisa Koohsarian, Athar Talebi, Mahshid Akhavan Rahnama, Mina Soufi Zomorrod, Saeid Kaviani, Arsalan Jalili
    Journal Paper , 2020 December 2, {Pages }

    Abstract

    Exosome‐based therapy is an emerging novel approach for myocardial infarction (MI) treatment. Exosomes are identified as extracellular vesicles that are produced within multi vesicular bodies in the cells cytosols and then are secreted from the cells. Exosomes are 30–100 nm in diameter that are released from viable cells and are different from other secreted vesicles such as apoptotic bodies and microvesicles in their origin and contents such as RNAs, proteins and nucleic acid. The recent advances in exosomes researches have demonstrated the role of these bio‐nanovesicles in the physiolocal, pathological and molecular aspects of the heart. The results of In vitro and preclinical models have shown that exosmes from different cardiac c

    Bioartificial injectable cartilage implants from demineralized bone matrix/PVA and related studies in rabbit animal model

    Neda Dadgar, Ali Ghiaseddin, Shiva Irani, Seyed Hossein Ahmadi Tafti, Mina Soufi-Zomorrod, Masoud Soleimani
    Journal PaperJournal of Biomaterials Applications , 2020 December 13, {Pages 0885328220976552 }

    Abstract

    Functional cartilage tissue engineering needs a substantial, easy to handle scaffold with proper mechanical strength to repair defected area in articular cartilage. In this study, we report the development and characterization of demineralized bone matrix (DBM) in with a poly vinyl alcohol (PVA) to have a proper homogenous injectable scaffold. Injectabiliy of the biodegradable scaffolds, degradation rate, swelling ratio compression and tensile mechanical properties, and viability and proliferation of bone marrow mesenchymal stem cells (BM-MSCs) followed by differentiation of them In-vitro and In-vivo seeded within the scaffold were studied. It demonstrated that the PVA 20% could increase significantly (p < 0.05) the biodegradability of

    Treatment protocols for BK virus associated hemorrhagic cystitis after hematopoietic stem cell transplantation

    Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod, Seyed Asadollah Mousavi
    Journal Paper , Volume 10 , Issue 5, 2020 January , {Pages 217 }

    Abstract

    Hematopoietic stem cell transplantation (HSCT) represents a vital curative choice for many disease. However its outcome can be hampered by a variety of transplant associated complications. Hemorrhagic cystitis (HC) considered as one of the major difficulties after HSCT. HC symptoms comprise hematuria, dysuria, burning during urination, urinary frequency, urgency and incontinency, abdominal or suprapubic pain, urinary obstruction, and renal or bladder damage. There are a lot of causes for HC development. BK virus reactivation is one of the major causes of HC after HSCT. There is still no standard and approved treatment protocol for BK virus associated HC (BKV-HC). Treatment of HC is according to the local standard operating procedures, depen

    Communication between stromal and hematopoietic stem cell by exosomes in normal and malignant bone marrow niche

    Journal Paper , 2020 January , {Pages }

    Abstract

    Combining Cell Therapy with Autologous Schwann Cell and Bone Marrow-derived Mesenchymal Stem Cell in Patients with Subacute Complete Spinal Cord Injury: Safety Considerations?…

    Saeed Oraee Yazdani, Mohammadhosein Akhlaghpasand, Maryam Golmohammadi, Maryam Hafizi, Mina Soufi Zomorrod, Nima Mohseni Kabir, Maryam Oraee-Yazdani, Alireza Zali, Masoud Soleimani
    Journal Paper , 2020 December 31, {Pages }

    Abstract

    Background Cellular transplantations have promising effects on treating spinal cord injury (SCI) patients. Safety alongside the complementary characteristics of Mesenchymal stem cells (MSC) and Schwann cells (SC) are suggested to be the two of the best candidates in SCI treatment. In this study, we assessed the safety and e cacy of intrathecal co-transplantation of autologous bone marrow MSC and SC in the patients with subacute traumatic complete SCI.Methods Eleven patients with complete SCI (American Spinal Injury Association Impairment Scale (AIS); grade A) were enrolled in this study during the subacute period of injury. The patients received intrathecal autologous combination of MSC and SC and were followed-up for 12 months. We assessed

    Combining Cell Therapy with Autologous Schwann Cell and Bone Marrow-derived Mesenchymal Stem Cell in Patients with Subacute Complete Spinal Cord Injury: Safety Considerations …

    SO Yazdani, M Akhlaghpasand, M Golmohammadi, M Hafizi, ...
    Journal Paper , , {Pages }

    Abstract

    The role of cardiac exosomes in myocardial repair at the glance.

    P Koohsarian, A Talebi, MA Rahnama, MS Zomorrod, S Kaviani, A Jalili
    Journal Paper , , {Pages }

    Abstract

    Electrospun triple‐layered PLLA/gelatin. PRGF/PLLA scaffold induces fibroblast migration

    Mehrdad Piran, Mahdi Shiri, Mahsa Soufi Zomorrod, Elaheh Esmaeili, Mina Soufi Zomorrod, Nader Vazifeh Shiran, Hossein Mahboudi, Hamed Daneshpazhouh, Naeimeh Dehghani, Simzar Hosseinzadeh
    Journal PaperJournal of cellular biochemistry , Volume 120 , Issue 7, 2019 July , {Pages 11441-11453 }

    Abstract

    The function of fibroblast cells in wounded areas results in reconstruction of the extra cellular matrix and consequently resolution of granulation tissue. It is suggested that the use of platelet‐rich plasma can accelerate the healing process in nonhealing or slow‐healing wounds. In this study, a simple and novel method has been used to fabricate an electrospun three‐layered scaffold containing plasma rich in growth factor with the aim of increasing the proliferation and migration of fibroblast cells in vitro. First, plasma rich in growth factor was derived from platelet rich plasma, and then a three‐layered scaffold was fabricated using PLLA nanofibers as the outer layers and plasma rich in growth factor‐containing gelatin fibe

    A critical role for miR-184 in the fate determination of oligodendrocytes

    Negin Afrang, Rezvan Tavakoli, Nooshin Tasharrofi, Amir Alian, Alireza Naderi Sohi, Mahboubeh Kabiri, Mehrnoosh Fathi-Roudsari, Mina Soufizomorrod, Farzad Rajaei, Masoud Soleimani, Fatemeh Kouhkan
    Journal PaperStem cell research & therapy , Volume 10 , Issue 1, 2019 December , {Pages 112 }

    Abstract

    New insights on cellular and molecular aspects of both oligodendrocyte (OL) differentiation and myelin synthesis pathways are potential avenues for developing a cell-based therapy for demyelinating disorders comprising multiple sclerosis. MicroRNAs (miRNA) have broad implications in all aspects of cell biology including OL differentiation. MiR-184 has been identified as one of the most highly enriched miRNAs in oligodendrocyte progenitor cells (OPCs). However, the exact molecular mechanism of miR-184 in OL differentiation is yet to be elucidated. Based on immunochemistry assays, qRT-PCR, and western blotting findings, we hypothesized that overexpression of miR-184 in either neural progenitor cells (NPCs) or embryonic mouse cortex stimulated

    Electroactive cardiac patch containing reduced graphene oxide with potential antibacterial properties

    Mohammad Hadi Norahan, Mohadeseh Pourmokhtari, Mohammad Reza Saeb, Bita Bakhshi, Mina Soufi Zomorrod, Nafiseh Baheiraei
    Journal PaperMaterials Science and Engineering: C , 2019 June 27, {Pages 109921 }

    Abstract

    Graphene based nanomaterials are promising candidates for cardiac tissue engineering due to the excellent electrical and mechanical properties and the robust surface chemistry. This research was designed to investigate the physicochemical and biological effects of increasing concentration of reduced graphene oxide (rGO) coating on collagen (Col) scaffolds as well as their antibacterial properties. Enhanced GO coating content to 400 μg/ml and its reduction showed improvement of HUVECs viability, however, following reduction of more GO concentration, decreased cell viability was observed. Compared with the Col counterpart, electroactive containing rGO scaffolds upregulated cardiac gene expression involve in electrical coupling (Cx43), musc

    Current Teaching

    • Ph.D.

      Advanced Cellular and Molecular Biology

    • Ph.D.

      Immunochemistry

    Teaching History

      Data not found
    • 2018
      Seifpour, Saba
      Expression analysis of long non coding RNA SNHG14 and its role in patients with non-M3 acute myeloid leukemia

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